A Comprehensive Picture of Vaginal Health
Vaginitis, characterized by discomfort, irritation, and odors, may be a sign of infection.
The NxGen MDx Vaginosis test uses a single swab with a 24-hour turnaround time to determine the cause of symptoms and provide a tailored treatment plan, getting you the relief you need.
Determining the Cause of Vaginitis Symptoms can be Challenging
Vaginitis can be caused by an imbalance of normal bacteria, yeast, or infectious pathogens such as STIs.
These types of infections have similar symptoms.
| Bacterial Vaginosis (BV) An overgrowth of naturally occurring vaginal bacteria |
Candidiasis An overgrowth of naturally occurring vaginal yeast |
Trichomoniasis The most common curable STI |
|
|---|---|---|---|
| Odor | Unpleasant | Unpleasant | Unpleasant |
| Vaginal Irritation | Sometimes | Often | Sometimes |
| Discharge | Thin, gray, white, or green | Thick, white | Frothy, gray, yellow, or green |
| External Appearance | Normal | Red and inflamed | Red and inflamed |
| Odor | |
|---|---|
| Bacterial Vaginosis | Unpleasant |
| Candidiasis | Unpleasant |
| Trichomoniasis | Unpleasant |
| Vaginal Irritation | |
|---|---|
| Bacterial Vaginosis | Sometimes |
| Candidiasis | Often |
| Trichomoniasis | Sometimes |
| Discharge | |
|---|---|
| Bacterial Vaginosis | Thin, gray, white, or green |
| Candidiasis | Thick, white |
| Trichomoniasis | Frothy, gray, yellow, or green |
| External Appearance | |
|---|---|
| Bacterial Vaginosis | Normal |
| Candidiasis | Red and inflamed |
| Trichomoniasis | Red and inflamed |
59% of patients with bacterial vaginosis have tried to self-treat before seeing their doctor, but most vaginal infections do not have over-the-counter treatment options.1
The NxGen MDx Vaginosis Test looks for 99%Â of the causes of community-acquired vaginal infections, helping your doctor distinguish between different types of infections without relying on symptoms alone.
NxGen’s test includes information on:
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- Bacterial vaginosis
- Aerobic vaginitis
- Yeast infections
- STIs
- Antibiotic resistance
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NxGen MDx is the Test of Choice, Even for Challenging Infections
Vaginal infections often recur and can be difficult for your doctor to effectively treat.
%
of infections have multiple pathogens present
%
of more than 9,000 cases showed evidence of antibiotic resistance²
Ask your doctor about the NxGen MDx Vaginosis Test for a fast solution to even the most complicated vaginitis cases.
NxGen MDx Makes the Testing Process Quick and Easy
The NxGen MDx Vaginosis Test uses a single swab to collect a sample from your vaginal wall. This test is quick, easy, and less invasive that a pap smear that requires a swab from your cervix.
When your doctor uses NxGen MDx, you also get:
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- Results in 24 hours
- Best-in-class customer service
- An affordable test with our Access for All program
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Leaving a Vaginal Infection Untreated May Lead to Further Health Complications
Bacterial Vaginosis
Increased risk for STIs, pelvic inflammatory disease, low birth weight, and premature birth3
Yeast
Discomfort, may interfere with pregnancy, and pain during sex4
Trichomoniasis
Increased risk of additional STIs, pelvic inflammatory disease, low birth weight, and premature birth5
The NxGen Vaginosis Test helps your doctor resolve your infection and reduce the risk of further health complications.
Don’t wait to call your doctor if something feels wrong.
Interested in the NxGen MDx Vaginosis Test?
Sources
2- NxGen MDx. 2021. Data on file.
3- Administration UD of VA Veterans Health. Bacterial Vaginosis – Women’s Health Guide – Public Health [Internet]. [cited 2021 Dec 1]. https://www.publichealth.va.gov/infectiondontpassiton/womens-health-guide/bacterial-vaginosis.asp
4- Untreated Yeast Infection: Why It Should Be Diagnosed and Treated [Internet]. Healthline. 2020 [cited 2021 Dec 1]. https://www.healthline.com/health/untreated-yeast-infection
5- Trichomoniasis [Internet]. Healthgrades. 2014 [cited 2021 Dec 1]. https://www.healthgrades.com/right-care/sexual-health/trichomoniasis
NxGen MDx Tests for 99% of Community-Acquired Infections
NxGen MDx’s Vaginosis Test takes the guesswork out of diagnosis by providing you with a comprehensive picture of your patient’s vaginal microbiome and infection.
An internal review of more than 9,000 vaginitis samples showed that 70% of positive cases were coinfections.* By comparison, less thorough testing would have failed to identify these complex cases, potentially leading to an ineffective treatment plan and recurrence.
Use NxGen MDx’s Vaginosis Test and give your patient the optimal treatment plan for their unique infection the first time.
NxGen MDx Performs Simultaneous Antibiotic Resistance Testing
66% of more than 9,000 cases showed evidence of antibiotic resistance*
According to the CDC…
“Each year in the U.S., at least 2.8 million people get an antibiotic-resistant infection…”1
Stop the revolving door of patients coming in again and again with recurrent vaginitis. NxGen empowers you to practice antibiotic stewardship by testing for resistance to 10 classes of antibiotics and getting you a result in 24 hours.
Use NxGen MDx’s Vaginosis Test to have confidence in a treatment plan that is appropriate for each infection.
Included in NxGen MDx’s Vaginosis Test
Pathogens and Antibiotic Resistance Tested
Normal Flora
- Lactobacillus crispatus
- Lactobacillus gasseri
- Lactobacillus iners
- Lactobacillus jensenii
Candida (Yeast Infection)
- Candida albicans
- Candida dubliniensis
- Candida glabrata
- Candida krusei
- Candida lusitaniae
- Candida parapsilosis
- Candida tropicalis
Sexually Transmitted Infection
- Chlamydia trachomatis
- Mycoplasma genitalium ^
- Neisseria gonorrhoeae
- Treponema pallidum (Syphilis)
- Haemophilus ducreyi
- Herpes Simplex Virus 1
- Herpes Simplex Virus 2
- Trichomonas vaginalis
Pathogens Associated with Vaginosis
- Atopobium vaginae
- Bacteroids fragilis
- Enterococcus faecalis
- Escherichia coli
- Gardnerella vaginalis
- Megasphaera Type 1
- Megasphaera Type 2
- Mobiluncus curtisii
- Mobiluncus mulieris
- Mycoplasma hominis
- Ureaplasma urealyticum
- Prevotella bivia
- Staphylococcus aureus
- Streptococcus agalactiae (Group B Strep)*
- Bacteria Vaginosis-Associated Bacterium 2 (BVAB2)
Antibiotic Resistance
- Betalactam/Beta-lactamase
- Inhibitor Combination Drugs
- Carbapenems
- Extended Spectrum Beta-lactams
- Macrolides
- Methicillin
- Nitroimidazoles
- Penicillins & Cephalosporins
- Quinolone/Fluoroquinolone
- Sulfamethoxazole & Trimethoprim (SMX/TMP)
- Vancomycin
*The NxGen MDx Group B Strep Test can be ordered as a stand alone test, using the same technology and providing results with the same accuracy.
^This pathogen will still be tested for even when the patient opts out of STIs.
Bolded pathogens are included in the dirty catch urine collection option.
Reflex fluconazole sensitivity testing is performed for samples positice for C. albicans, C. dubliniensis, C. lusitaniae, C. parapsilosis, and C. tropicalis. As most C. glabrata and C. krusei isolates demonstrate fluconazole resistance, alternative treatment options are provided.
Vaginitis in Pregnant & Pediatric Patients
Untreated Vaginal Infections Impact Reproductive Health2,3
- Infertility
- Endometriosis
- Increased risk of acquiring STIs (including HIV)
- Preterm birth
- Neonatal sepsis
- Low birth weight
- Pelvic Inflammatory Disease
- Ventilation/respiratory distress in infants
Vaginitis is Common in Pediatric and Adolescent Patients4
50% of new STIs are in individuals under the age of 255. NxGen MDx offers a dirty catch urine collection option for pediatric patients and individuals for whom a vaginal wall swab is not an option.
- 10 pathogens
- Sexually Transmitted Infections (STIs)
- Yeast Infections
- Antibiotic Resistance (ABR)
The NxGen MDx Vaginosis Test Impacts Patient Care
The additional assistance with antibiotic resistance testing has also been beneficial as we have been able to treat appropriately to ensure patients will not have to repeat the evaluation as well as not having to take unnecessary medications.
The ability to evaluate normal flora has been so valuable and helps give us better direction when developing treatment plans.
Excellent customer service and any question or concern is always addressed in less than twenty-four hours. Thank you NxGen MDx!
With this comprehensive knowledge and quick turnaround time, I am able to treat my patients quickly and effectively, which creates an atmosphere of trust and reliability.
For years I felt limited to the testing that was available; however, the NxGen MDx swab testing evaluated my patient as a whole and ultimately limits the number of times my patients needs to come back for further testing and evaluation. We are able to treat the patient more effectively and quickly using this swab.
I have been using the NxGen MDx testing swab to diagnose vaginitis for the past 2-3 years. I have enjoyed the thoroughness of the swab that it will test for aerobic and anaerobic microorganisms at the same time as well as STI organisms.
The best part is the vaginosis panel includes treatment options and a resistance table to eliminate treatment failure.
The NxGen Vaginosis swab/panel allows me to get a complete analysis of the vaginal flora as well as any pathogenic organisms present. It also provides sensitivity for any pathogenic organisms, so patients are treated with the most effective course of action from the start.
The [NxGen MDx Vaginosis Test] is so easy to use and interpret, and the turnaround time is unbeatable. It has made such a difference for our patients who have struggled with recurrent infections to identify organisms that are not included in other swabs.
NxGen MDx Provides More than Just Results
Connect With Us
If you are interested in offering the NxGen MDx Vaginosis Test or simply want to learn more, click the button below to contact a NxGen representative.
Sources
*NxGen MDx. 2021. Data on file.
1- https://www.cdc.gov/drugresistance/index.htmlÂ
2- Ravel J, Moreno I, Simón C. Bacterial vaginosis and its association with infertility, endometritis, and pelvic inflammatory disease. American Journal of Obstetrics & Gynecology. 2021 Mar 1;224(3):251–7.Â
3- STD Facts – STDs & Pregnancy Detailed Fact Sheet [Internet]. 2021 [cited 2021 Dec 20]. https://www.cdc.gov/std/pregnancy/stdfact-pregnancy-detailed.htm
4- Vulvovaginitis- presentation of more common problems in pediatric and adolescent gynecology (https://pubmed.ncbi.nlm.nih.gov/28927766/)
5- Sexually Transmitted Infections Prevalence, Incidence, and Cost Estimates in the United States (https://www.cdc.gov/std/statistics/prevalence-incidence-cost-2020.htm)
Patient FAQs
What is vaginitis/vaginosis?
Vaginitis and vaginosis are broad characterizations of different vaginal infections that can cause symptoms such as odor, vaginal irritation, and discharge.
What is an STI?
An STI, or sexually transmitted infection, is a pathogen that is transmitted via sexual intercourse or contact.
What should I do if I'm experiencing symptoms of vaginitis/vaginosis or STIs?
You should consult your doctor for testing and treatment.
How quickly can I expect my infection to get better?
NxGen MDx test results will be ready within 1 day of sample receipt. From there, your doctor will prescribe targeted antibiotics that typically resolve infections within a week.
How can I avoid future infections?
STIs can be avoided by using protection methods, such as condoms, that can prevent transmission of infections in addition to pregnancy. Avoiding douching, certain soaps, and underwear fabric types can also prevent future instances of vaginosis or yeast infections.
Is the testing process difficult?
No, it is just a simple swab on the inside walls of the vagina, less invasive than a pap smear.
Provider FAQs
What is the justification for such a broad panel?
Data from our testing has found that 70% of positive cases have more than one pathogen present and 40% of positive cases have additional pathogens that would change treatment methods from typical BV.
How is billing for the test handled?
You just need to offer patients the option of using self-pay or insurance. From there, NxGen MDx will walk patients through the rest of the billing process.
What is the TAT for the test?
Test results will be available within 24 hours of sample receipt in our lab. NxGen MDx provides multiple ways of receiving results (from faxing to EMR integration) or can send results directly to patients.
What happens if the patient tests negative but is still symptomatic?
16S rRNA sequencing is available for identification of pathogenic bacteria when none were identified on the array and Lactobacillus spp. is displaced.