A Comprehensive Picture of Vaginal Health

Vaginitis, characterized by discomfort, irritation, and odors, may be a sign of infection.

The NxGen MDx Vaginosis test uses a single swab with a 24-hour turnaround time to determine the cause of symptoms and provide a tailored treatment plan, getting you the relief you need.

Determining the Cause of Vaginitis Symptoms can be Challenging

Vaginitis can be caused by an imbalance of normal bacteria, yeast, or infectious pathogens such as STIs.

These types of infections have similar symptoms.

Bacterial Vaginosis (BV)
An overgrowth of naturally occurring vaginal bacteria
An overgrowth of naturally occurring vaginal yeast
The most common curable STI
Odor Unpleasant Unpleasant Unpleasant
Vaginal Irritation Sometimes Often Sometimes
Discharge Thin, gray, white, or green Thick, white Frothy, gray, yellow, or green
External Appearance Normal Red and inflamed Red and inflamed
Bacterial Vaginosis Unpleasant
Candidiasis Unpleasant
Trichomoniasis Unpleasant
Vaginal Irritation
Bacterial Vaginosis Sometimes
Candidiasis Often
Trichomoniasis Sometimes
Bacterial Vaginosis Thin, gray, white, or green
Candidiasis Thick, white
Trichomoniasis Frothy, gray, yellow, or green
External Appearance
Bacterial Vaginosis Normal
Candidiasis Red and inflamed
Trichomoniasis Red and inflamed

59% of patients with bacterial vaginosis have tried to self-treat before seeing their doctor, but most vaginal infections do not have over-the-counter treatment options.1

The NxGen MDx Vaginosis Test looks for 99% of the causes of community-acquired vaginal infections, helping your doctor distinguish between different types of infections without relying on symptoms alone.

NxGen’s test includes information on:

      • Bacterial vaginosis
      • Aerobic vaginitis
      • Yeast infections
      • STIs
      • Antibiotic resistance

NxGen MDx is the Test of Choice, Even for Challenging Infections

Vaginal infections often recur and can be difficult for your doctor to effectively treat.


of infections have multiple pathogens present


of more than 9,000 cases showed evidence of antibiotic resistance²

Ask your doctor about the NxGen MDx Vaginosis Test for a fast solution to even the most complicated vaginitis cases.

NxGen MDx Makes the Testing Process Quick and Easy

Vaginal pathogens can be collected with a swab from the vaginal wall.

Leaving a Vaginal Infection Untreated May Lead to Further Health Complications

Bacterial Vaginosis

Increased risk for STIs, pelvic inflammatory disease, low birth weight, and premature birth3


Discomfort, may interfere with pregnancy, and pain during sex4


Increased risk of additional STIs, pelvic inflammatory disease, low birth weight, and premature birth5

The NxGen Vaginosis Test helps your doctor resolve your infection and reduce the risk of further health complications.

Don’t wait to call your doctor if something feels wrong.

Interested in the NxGen MDx Vaginosis Test?

NxGen MDx Tests for 99% of Community-Acquired Infections

NxGen MDx’s Vaginosis Test takes the guesswork out of diagnosis by providing you with a comprehensive picture of your patient’s vaginal microbiome and infection.

An internal review of more than 9,000 vaginitis samples showed that 70% of positive cases were coinfections.* By comparison, less thorough testing would have failed to identify these complex cases, potentially leading to an ineffective treatment plan and recurrence.

NxGen Vaginosis Test shows 70% of positive cases included more than 1 pathogen.

Use NxGen MDx’s Vaginosis Test and give your patient the optimal treatment plan for their unique infection the first time.

NxGen MDx Performs Simultaneous Antibiotic Resistance Testing

66% of more than 9,000 cases showed evidence of antibiotic resistance*

According to the CDC…

“Each year in the U.S., at least 2.8 million people get an antibiotic-resistant infection…”1

Stop the revolving door of patients coming in again and again with recurrent vaginitis. NxGen empowers you to practice antibiotic stewardship by testing for resistance to 10 classes of antibiotics and getting you a result in 24 hours.

Use NxGen MDx’s Vaginosis Test to have confidence in a treatment plan that is appropriate for each infection.

Included in NxGen MDx’s Vaginosis Test

Pathogens and Antibiotic Resistance Tested

Normal Flora

  • Lactobacillus crispatus
  • Lactobacillus gasseri
  • Lactobacillus iners
  • Lactobacillus jensenii

Candida (Yeast Infection)

  • Candida albicans
  • Candida dubliniensis
  • Candida glabrata
  • Candida krusei
  • Candida lusitaniae
  • Candida parapsilosis
  • Candida tropicalis

Sexually Transmitted Infection

  • Chlamydia trachomatis
  • Mycoplasma genitalium ^
  • Neisseria gonorrhoeae
  • Treponema pallidum (Syphilis)
  • Haemophilus ducreyi
  • Herpes Simplex Virus 1
  • Herpes Simplex Virus 2
  • Trichomonas vaginalis

Pathogens Associated with Vaginosis

  • Atopobium vaginae
  • Bacteroids fragilis
  • Enterococcus faecalis
  • Escherichia coli
  • Gardnerella vaginalis
  • Megasphaera Type 1
  • Megasphaera Type 2
  • Mobiluncus curtisii
  • Mobiluncus mulieris
  • Mycoplasma hominis
  • Ureaplasma urealyticum
  • Prevotella bivia
  • Staphylococcus aureus
  • Streptococcus agalactiae (Group B Strep)*
  • Bacteria Vaginosis-Associated Bacterium 2 (BVAB2)

Antibiotic Resistance

  • Betalactam/Beta-lactamase
  • Inhibitor Combination Drugs
  • Carbapenems
  • Extended Spectrum Beta-lactams
  • Macrolides
  • Methicillin
  • Nitroimidazoles
  • Penicillins & Cephalosporins
  • Quinolone/Fluoroquinolone
  • Sulfamethoxazole & Trimethoprim (SMX/TMP)
  • Vancomycin

*The NxGen MDx Group B Strep Test can be ordered as a stand alone test, using the same technology and providing results with the same accuracy.

^This pathogen will still be tested for even when the patient opts out of STIs.

Bolded pathogens are included in the dirty catch urine collection option.

Reflex fluconazole sensitivity testing is performed for samples positice for C. albicans, C. dubliniensis, C. lusitaniae, C. parapsilosis, and C. tropicalis. As most C. glabrata and C. krusei isolates demonstrate fluconazole resistance, alternative treatment options are provided.

Vaginitis in Pregnant & Pediatric Patients

Untreated Vaginal Infections Impact Reproductive Health2,3

  • Infertility
  • Endometriosis
  • Increased risk of acquiring STIs (including HIV)
  • Preterm birth
  • Neonatal sepsis
  • Low birth weight
  • Pelvic Inflammatory Disease
  • Ventilation/respiratory distress in infants

Vaginitis is Common in Pediatric and Adolescent Patients4

50% of new STIs are in individuals under the age of 255NxGen MDx offers a dirty catch urine collection option for pediatric patients and individuals for whom a vaginal wall swab is not an option.

  • 10 pathogens
  • Sexually Transmitted Infections (STIs)
  • Yeast Infections
  • Antibiotic Resistance (ABR)

The NxGen MDx Vaginosis Test Impacts Patient Care

The additional assistance with antibiotic resistance testing has also been beneficial as we have been able to treat appropriately to ensure patients will not have to repeat the evaluation as well as not having to take unnecessary medications.

Erika Biggs


The ability to evaluate normal flora has been so valuable and helps give us better direction when developing treatment plans.

Avery Klepacki


Excellent customer service and any question or concern is always addressed in less than twenty-four hours. Thank you NxGen MDx!

Leslie Biggs

NP, Peachtree Internal Medicine

With this comprehensive knowledge and quick turnaround time, I am able to treat my patients quickly and effectively, which creates an atmosphere of trust and reliability.

Elizabeth Fondren


For years I felt limited to the testing that was available; however, the NxGen MDx swab testing evaluated my patient as a whole and ultimately limits the number of times my patients needs to come back for further testing and evaluation. We are able to treat the patient more effectively and quickly using this swab.

Melissa Craig


I have been using the NxGen MDx testing swab to diagnose vaginitis for the past 2-3 years. I have enjoyed the thoroughness of the swab that it will test for aerobic and anaerobic microorganisms at the same time as well as STI organisms.

Melissa Craig


The best part is the vaginosis panel includes treatment options and a resistance table to eliminate treatment failure.

Leslie Biggs

NP, Peachtree Internal Medicine

The NxGen Vaginosis swab/panel allows me to get a complete analysis of the vaginal flora as well as any pathogenic organisms present. It also provides sensitivity for any pathogenic organisms, so patients are treated with the most effective course of action from the start.

Elizabeth Fondren


The [NxGen MDx Vaginosis Test] is so easy to use and interpret, and the turnaround time is unbeatable. It has made such a difference for our patients who have struggled with recurrent infections to identify organisms that are not included in other swabs.

Avery Klepacki


NxGen MDx Provides More than Just Results

NxGen offers one swab testing, access for all, 24-hour TAT, treatment options, excellent customer service, 24/7 portal access, expert advice, and 16S sequencing.

Connect With Us

If you are interested in offering the NxGen MDx Vaginosis Test or simply want to learn more, click the button below to contact a NxGen representative.

Patient FAQs

What is vaginitis/vaginosis?

Vaginitis and vaginosis are broad characterizations of different vaginal infections that can cause symptoms such as odor, vaginal irritation, and discharge.

What is an STI?

An STI, or sexually transmitted infection, is a pathogen that is transmitted via sexual intercourse or contact.

What should I do if I'm experiencing symptoms of vaginitis/vaginosis or STIs?

You should consult your doctor for testing and treatment.

How quickly can I expect my infection to get better?

NxGen MDx test results will be ready within 1 day of sample receipt. From there, your doctor will prescribe targeted antibiotics that typically resolve infections within a week.

How can I avoid future infections?

STIs can be avoided by using protection methods, such as condoms, that can prevent transmission of infections in addition to pregnancy. Avoiding douching, certain soaps, and underwear fabric types can also prevent future instances of vaginosis or yeast infections.

Is the testing process difficult?

No, it is just a simple swab on the inside walls of the vagina, less invasive than a pap smear.

Provider FAQs

What is the justification for such a broad panel?

Data from our testing has found that 70% of positive cases have more than one pathogen present and 40% of positive cases have additional pathogens that would change treatment methods from typical BV.

How is billing for the test handled?

You just need to offer patients the option of using self-pay or insurance. From there, NxGen MDx will walk patients through the rest of the billing process.

What is the TAT for the test?

Test results will be available within 24 hours of sample receipt in our lab. NxGen MDx provides multiple ways of receiving results (from faxing to EMR integration) or can send results directly to patients.

What happens if the patient tests negative but is still symptomatic?

16S rRNA sequencing is available for identification of pathogenic bacteria when none were identified on the array and Lactobacillus spp. is displaced.