The Early Advantage Panel

Carrier screening can help inform life-saving interventions and improve quality of life for your newborn. Find out if you carry an inherited genetic condition that could affect your child.

Carrier Screening Can Provide You With Options

Actionable Information When Planning for Your Family

All newborns in the United States undergo screening for genetic conditions. With carrier screening you can get actionable information about your child's risk for a genetic condition before birth instead of after. When performed before or during pregnancy, the Early Advantage Panel allows you and your healthcare provider to:

  • Know your child's risk of inherited genetic conditions
  • Improve preconception, pregnancy, and postnatal planning
  • Explore all your options
  • Better manage your pregnancy
  • Choose the right birthing team and location
  • Get an earlier diagnosis and timely treatment

Every baby in the U.S. receives newborn screening. By screening for these conditions before birth, you can minimize surprise newborn screening results.

If both you and your partner are carriers for the same condition, there are options available to you based on where you are in your reproductive journey.

Carrier screening is simple and convenient, requiring only a blood draw or saliva sample taken at your doctors office. Your results are normally available in 7 to 10 days.

What is Carrier Screening?

Carrier screening is a DNA test that can determine if you are a carrier for a genetic condition. DNA typically contains 2 copies of every gene, one inherited from mom and one from dad. A variant is a change in a gene that could cause a genetic condition. While many people carry variants, most carriers are typically healthy.

Two reproductive partners who both carry the same autosomal recessive condition have a 25% chance of having an affected child. With X-linked conditions, if the mother is a carrier, there is a 50% chance that male children will be affected.

Autosomal Recessive Inheritance

X-Linked Inheritance

What is in the Early Advantage Panel?

The Early Advantage Panel is the first panel of its size to include all 35 conditions that are recommended but the U.S. Department of Health and Human Services to be done during newborn screening. This list of conditions is known as the Recommended Uniform Screening Panel (RUSP). While newborn screening is important, by looking for these recommended conditions either before or during pregnancy you can increase your available options. It also screens for other conditions that are recommended by other leading medical organizations.

RUSP conditions are bolded

  • 21-Hydroxylase-Deficient Congenital Adrenal Hyperplasia
  • Beta-Thalassemia
  • Bloom Syndrome
  • Canavan Disease
  • Cystic Fibrosis and CFTR-Related Disorders
  • Dihydrolipoamide Dehydrogenase Deficiency
  • DMD-Related Dystrophinopathy (Duchenne Muscular Dystrophy and Becker Muscular Dystrophy
  • Familial Dysautonomia
  • Familial Hyperinsulinism, ABCC8-Related
  • Fanconi Anemia Type C
  • Fragile X and FMR1-Related Disorders
  • FKTN-Related Disorders (Including Walker-Warburg Syndrome)
  • Gaucher Disease
  • Glycogen Storage Disease Type IA
  • Glycogen Storage Disease Type II (Pompe Disease)
  • Glycogen Storage Disease Type IV/Adilt Polyglucosan Body Disease
  • Joubert Syndrome 2/TMEM216-Related Disorders
  • Maple Syrup Urine Disease Type 1A
  • Maple Syrup Urine Disease Type 1B
  • Metachromatic Leukodystrophy, ARSA-Related
  • Mucolipidosis IV
  • Nemaline Myopathy 2
  • Niemann-Pick Disease Type A/B
  • SLC26A2-Related Disorders
  • Sickle Cell (HbS) and HbC Disease
  • Spinal Muscular Atrophy
  • Tay-Sachs Disease
  • Usher Syndrome Type IF/PCDH15-Related Disorders
  • Usher Syndrome Type IIIA
  • Usher Syndrome Type IB/MYO7A-Related Disorders
  • Usher Syndrome Type ID/CDH23-Related Disorders
  • Wilson Disease
  • 3-Hydroxy-3-Methylglutaryl-CoA (HMG-CoA) Lyase Deficiency
  • 3-Methylcrotonyl-CoA Carboxylase (3-MCC) Deficiency, MCCC-1/MCCC-2-Related
  • ADA-Related Conditions
  • Alpha-Thalassemia/Alpha-Globin Triplication
  • Argininosuccinic Aciduria
  • Beta-Ketothiolase Deficiency
  • Biotinidase Deficiency
  • Carnitine Palmitoyltransferase II Deficiency
  • Citrin Deficiency
  • Citrullinemia Type 1
  • Congenital Disorder of Glycolysation, PMM-2-Related
  • Galactokinase Deficiency
  • Galactosemia, GALT-Related
  • Glucose-6-Phosphate Dehydrogenase Deficiency
  • Glutaric Acidemia Type 1
  • Holocarboxylase Synthetase Deficiency
  • Homocystinuria, Cobalamin E Type
  • Homocystinuria due to Cystathionine Beta-Synthase Deficiency
  • Isovaleric Acidemia
  • Krabbe Disease
  • Long Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency
  • Medium Chain Acyl-CoA Dehydrogenase Deficiency
  • Methylmalonic Acidemia, MMAA/MMAB-Related
  • Methylmalonic Acidemia with Homocystinuria, Cobalamin C Type
  • Methylmalonic Acidemia with Homocystinuria, Cobalamin D Type
  • Mucopolysaccharidosis Type 1 (Hurler Syndrome)
  • Nonsyndromic Hearing Loss
  • Pendred Syndrome
  • Phenylalanine Hydroxylase Deficiency
  • Polycystic Kidney Disease, Autosomal Recessive
  • Primary Carnitine Deficiency
  • Propionic Acidemia, PCCA/PCCB-Related
  • Smith-Lemli-Opitz Syndrome
  • Tyrosinemia Type 1
  • Tyrosinemia Type 2
  • Usher Syndrome Type IIA/USH2A-Related Disorders
  • Very Long-Chain Acyl-CoA Dehydrogenase Deficiency
  • X-Linked Adrenoleukodystrophy

Did the Early Advantage Panel Help with Pregnancy Planning?

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Get answers to all your questions related to billing, insurance coverage, the status of your screening results, and more by calling us at (855) 776-9436 or clicking the link below.

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