The Super Panel

Begin your reproductive journey with carrier screening to determine your risk of passing on inherited genetic conditions to your child.

What is Carrier Screening?

Carrier screening looks at your DNA to determine if you are a carrier of any autosomal recessive conditions (such as cystic fibrosis) or X-linked conditions (such as Fragile X). Carriers are generally healthy and typically don't show symptoms. However, if both reproductive partners are carriers of the same condition, there is a risk their baby could be affected by it.

Two reproductive partners who both carry the same autosomal recessive condition have a 25% chance of having a child affected by that condition. With X-linked conditions, if the mother is a carrier, there is a 50% chance that male children will be affected by that condition.

Autosomal Recessive Inheritance

X-Linked Inheritance

Learn About Your Reproductive Risk with the Super Panel

1 in 300 pregnancies will be impacted by a genetic condition.1 Even if you have no family history of genetic conditions, the risk still exists. In fact, 80% of babies born with a genetic condition have no known family history of it.2 The Super Panel screens for 147 genetic conditions that are common across multiple ethnicities, regardless of family history. This includes conditions that are federally recommended for newborn screening (NBS).

When performed before or during pregnancy, the Super Panel allows you and your healthcare provider to:

  • Know your child's risk of inherited genetic conditions
  • Improve preconception, pregnancy, and postnatal planning
  • Explore all your options
  • Better manage your pregnancy
  • Choose the right birthing team and location
  • Get an earlier diagnosis and timely treatment

Every baby in the U.S. receives newborn screening. By screening for these conditions before birth, you can minimize surprise newborn screening (NBS) results.

If both you and your partner are carriers for the same condition, there are different options available to you based on where you are in your reproductive journey.

Carrier screening is simple and convenient, requiring only a blood draw or saliva sample taken at your provider's office. Your results will be available in approximately 2 weeks from sample receipt.

Carrier Screening Can Provide You With Options

Conditions on the Super Panel

  • 3-Beta-Hydroxysteroid Dehydrogenase Type II Deficiency (Congenital Adrenal Hyperplasia)
  • 3-Hydroxy-3-Methylglutaryl-CoA (HMG-CoA) Lyase Deficiency
  • 3-Methylcrotonyl-CoA Carboxylase (3-MCC) Deficiency, MCCC1, MCC2-Related
  • 3-Methylglutaconic Aciduria Type III (Costeff Optic Atrophy)
  • 11-Beta-Hydroxylase-Deficient Congenital Adrenal Hyperplasia
  • 17-Alpha-Hydroxylase-Deficient Congenital Adrenal Hyperplasia
  • 21-Hydroxylase-Deficient Congenital Adrenal Hyperplasia
  • Abetalipoproteinemia
  • Achromatopsia
  • ADA-Related Conditions
  • Alkaptonuria
  • Alpha-Thalassemia/Alpha-Globin Triplication
  • Alpha-Mannosidosis
  • Alport Syndrome, COL4A4-Related
  • Andermann Syndrome
  • Argininosuccinic Aciduria
  • Arthrogryposis, Mental Retardation, and Seizures (AMRS)
  • Aspartylglucosaminuria
  • Ataxia-Telangiectasia
  • Ataxia With Vitamin E Deficiency
  • Autoimmune Polyendocrinopathy with Candidiasis and Ectodermal Dystrophy
  • Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS)
  • Bardet-Biedl Syndrome, BBS1-Related
  • Bardet-Biedl Syndrome, BBS10-Related
  • Bardet-Biedl Syndrome, MKKS-Related
  • Beta-Ketothiolase Deficiency
  • Beta-Thalassemia
  • Biotinidase Deficiency
  • Bloom Syndrome
  • Canavan Disease
  • Carnitine Palmitoyltransferase I Deficiency
  • Carnitine Palmitoyltransferase II Deficiency
  • Cartilage-Hair Hypoplasia, Anauxetic Dysplasia Spectrum Disorders
  • Choroideremia
  • Citrin Deficiency
  • Citrullinemia Type 1
  • Cohen Syndrome
  • Combined Pituitary Hormone Deficiency
  • Congenital Amegakaryocytic Thrombocytopenia
  • Congenital Disorder of Glycosylation Type Ia
  • Congenital Disorder of Glycosylation Type Ib
  • Cystic Fibrosis and Other CFTR-Related Disorders
  • Cystinosis
  • D-Bifunctional Protein Deficiency
  • DHDDS-Related Disorders (including Retinitis Pigmentosa 59)
  • Dihydrolipoamide Dehydrogenase Deficiency
  • Dihydropyrimidine Dehydrogenase Deficiency
  • DMD-Related Dystrophinopathy (Duchenne Muscular Dystrophy and Becker Muscular Dystrophy)
  • Dyskeratosis Congenita
  • Ehlers-Danlos Syndrome, Dermatosparaxis Type
  • Familial Dysautonomia
  • Familial Hyperinsulinism, ABCC8-Related
  • Familial Mediterranean Fever
  • Fanconi Anemia Type C
  • FKTN-Related Disorders (Including Walker-Warburg Syndrome)
  • Fragile X and FMR1-Related Disorders
  • Galactokinase Deficiency
  • Galactosemia, GALT-Related
  • Gaucher Disease
  • Glucose-6-Phosphate Dehydrogenase Deficiency
  • Glutaric Acidemia Type 1
  • Glycine Encephalopathy, AMT-Related
  • Glycine Encephalopathy, GLDC-Related
  • Glycogen Storage Disease Type IA
  • Glycogen Storage Disease Type IB
  • Glycogen Storage Disease Type II (Pompe Disease)
  • Glycogen Storage Disease Type III
  • Glycogen Storage Disease Type IV/Adult Polyglucosan Body Disease
  • Glycogen Storage Disease Type V
  • GRACILE Syndrome/BCS1L-Related Disorders
  • Hemophilia C/Factor XI Deficiency
  • Hereditary Fructose Intolerance
  • Holocarboxylase Synthetase Deficiency
  • Homocystinuria Due to Cystathionine Beta-Synthase Deficiency
  • Homocystinuria, Cobalamin E Type
  • Hypophosphatasia
  • Inclusion Body Myopathy 2
  • Isovaleric Acidemia
  • Joubert Syndrome 2/TMEM216-Related Disorders
  • Junctional Epidermolysis Bullosa, LAMA3-Related
  • Junctional Epidermolysis Bullosa, LAMB3-Related
  • Junctional Epidermolysis Bullosa, LAMC2-Related
  • Krabbe Disease
  • Limb-Girdle Muscular Dystrophy Type 2A
  • Limb-Girdle Muscular Dystrophy Type 2D
  • Limb-Girdle Muscular Dystrophy Type 2E
  • Lipoid Congenital Adrenal Hyperplasia, STAR-Related
  • Long Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency
  • Lysosomal Acid Lipase Deficiency
  • Maple Syrup Urine Disease Type 1A
  • Maple Syrup Urine Disease Type 1B
  • Medium Chain Acyl-CoA Dehydrogenase Deficiency
  • Megalencephalic Leukoencephalopathy with Subcortical Cysts Type 1:
  • Metachromatic Leukodystrophy, ARSA-Related
  • Methylmalonic Acidemia with Homocystinuria, Cobalamin C Type
  • Methylmalonic Acidemia with Homocystinuria, Cobalamin D Type:
  • Methylmalonic Acidemia, MMAA, MMAB-Related
  • Mucolipidosis IV
  • Mucopolysaccharidosis Type I (Hurler Syndrome)
  • Multiple Sulfatase Deficiency
  • Nemaline Myopathy 2
  • Nephrotic Syndrome/Congenital Finnish Nephrosis, NPHS1-Related
  • Nephrotic Syndrome/Steroid-Resistant Nephrotic Syndrome, NPHS2-Related
  • Neuronal Ceroid Lipofuscinosis, CLN3-Related
  • Neuronal Ceroid Lipofuscinosis, CLN5-Related
  • Neuronal Ceroid Lipofuscinosis, PPT1-Related
  • Neuronal Ceroid Lipofuscinosis, TPP1-Related
  • Neuronal Ceroid Lipofuscinosis/Northern Epilepsy, CLN8-Related
  • Niemann-Pick Disease Type A/B
  • Niemann-Pick Type C, NPC1-Related
  • Nijmegen Breakage Syndrome
  • Nonsyndromic Hearing Loss GJB2/GJB3/GJB6- Related
  • Pendred Syndrome
  • Phenylalanine Hydroxylase Deficiency
  • Phosphoglycerate Dehydrogenase Deficiency/Neu-Laxova Syndrome
  • Polycystic Kidney Disease, Autosomal Recessive
  • POMGNT1-Related Disorders
  • Primary Carnitine Deficiency
  • Primary Hyperoxaluria Type 1, AGXT-Related
  • Primary Hyperoxaluria Type 2, GRHPR-Related
  • Propionic Acidemia, PCCA-Related
  • Propionic Acidemia, PCCB-Related
  • Pseudocholinesterase Deficiency
  • Pycnodysostosis
  • Rhizomelic Chondrodysplasia Punctata Type 1/Refsum Disease
  • Short Chain Acyl-CoA Dehydrogenase Deficiency
  • Sialic Acid Storage Disorders
  • Sickle Cell (HbS) and HbC Disease
  • Sjögren-Larsson Syndrome
  • SLC26A2-Related Disorders
  • Smith-Lemli-Opitz Syndrome
  • Spinal Muscular Atrophy
  • Tay-Sachs Disease
  • Tyrosine Hydroxylase Deficiency
  • Tyrosinemia Type I
  • Tyrosinemia Type II
  • Usher Syndrome Type IB/MYO7A-Related Disorders
  • Usher Syndrome Type ID/CDH23-Related Disorders
  • Usher Syndrome Type IF/PCDH15-Related Disorders
  • Usher Syndrome Type IIA/USH2A-Related Disorders
  • Usher Syndrome Type IIIA
  • Very Long-Chain Acyl-CoA Dehydrogenase Deficiency
  • Wilson Disease
  • X-Linked Adrenoleukodystrophy
  • X-Linked Congenital Adrenal Hypoplasia
  • X-Linked Juvenile Retinoschisis
  • Zellweger Syndrome Spectrum, PEX1-Related

Did you get the Super Panel? Tell Your Story!

"The genetic counselor I had was very knowledgable and eased my mind on all potential questions! Was courteous and professional and made sure no stone was left unturned with potential risks. Very happy I got the tests!" - Riley

Connect With Our Customer Care Center

Get answers to all your questions related to billing, insurance coverage, the status of your screening results, and more by calling us at (855) 776-9436 or clicking the link below.

Connect With Our  Customer Care Center

1. Johansen Taber KA, Beauchamp KA, Lazarin GA, Muzzey D, Arjunan A, Goldberg JD. Clinical utility of expanded carrier screening: results-guided actionability and outcomes. Genet Med. 2019 May;21(5):1041–8.
2. Blythe SA, Farrell PM. Advances in the diagnosis and management of cystic fibrosis. Clin Biochem. 1984 Oct;17(5):277–83.