NxGen MDx White Papers

NxGen MDx LLC is the leading laboratory for precise genetic carrier screening. Unlike other laboratories, NxGen’s technology examines the entire gene rather than parts of the gene, giving families a comprehensive assessment of their true risk. With over 99% accuracy, doctors rely on our best-in-class genetic screening as trusted tools for early family planning. Let us give you and your patients peace of mind and the knowledge to plan for the years ahead, just like we’ve provided for so many other individuals and families.

Below are whitepapers that we publish periodically to demonstrate our commitment to constantly improving genetic carrier screening.

NxGen MDx White Papers

White Paper: Cystic Fibrosis (CF) & CFTR

Cystic fibrosis (CF) is a fatal hereditary disease in the U.S. CF is a disorder of the cells that line the lungs, small intestines, sweat glands, and pancreas. The current average life expectancy for someone with CF is 37 years. Cystic fibrosis is caused by variants in the CF transmembrane regulator (CFTR) gene, located on the long arm of chromosome 7. An individual who inherits two pathogenic variants in the CFTR gene will have CF or a CFTR-related disorder. Twelve million Americans, or 1 in 25, are symptomless carriers of pathogenic variants in the CFTR gene, making it the most common genetic disorder in the U.S.